HeLa cells were subjected to SDS PAGE followed by western blot with FNab06102(PACSIN3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06102(PACSIN3 antibody) at dilution of 1:100
Background
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity(By similarity).