Products

anti- PACSIN2 antibody

FNab06101 Catalogue No.
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, IHC, WB, IP
Product Information
Product Name
anti- PACSIN2 antibody
Catalogue No.
FNab06101
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Immunogen Information
Immunogen
protein kinase C and casein kinase substrate in neurons 2
Observed MW
60-65 kDa
Application
Tested Application
ELISA, IHC, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Uniprot information
UniProt ID
Q9UNF0
Images
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06101(PACSIN2 Antibody) at dilution of 1:400
IP Result of anti-PACSIN2 (IP:FNab06101, 4ug; Detection:FNab06101 1:500) with NIH/3T3 cells lysate 1200ug.
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab06101(PACSIN2 Antibody) at dilution of 1:600