Products
PACSIN2 antibody
- Product Name
- PACSIN2 antibody
- Catalogue No.
- FNab06101
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein kinase C and casein kinase substrate in neurons 2
- UniProt ID
- Q9UNF0
- Observed MW
- 60-65 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab06101(PACSIN2 Antibody) at dilution of 1:600
IP Result of anti-PACSIN2 (IP:FNab06101, 4ug; Detection:FNab06101 1:500) with NIH/3T3 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06101(PACSIN2 Antibody) at dilution of 1:400
- Background
- Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
