Products
p70S6K antibody
- Product Name
- p70S6K antibody
- Catalogue No.
- FNab06090
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Alternative Names
- P70 alpha antibody, p70 ribosomal S6 kinase alpha antibody, p70 S6 kinase alpha antibody, p70 S6K 1 antibody, p70 S6K alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70S6K antibody, P70S6K1 antibody, PS6K antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K beta 1 antibody, S6K1 antibody, STK14A antibody
- UniProt ID
- P23443
- Observed MW
- 65-70 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP, FC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06090(p70(S6K) antibody) at dilution of 1:1200
IP Result of anti-p70S6K (IP:FNab06090, 3ug; Detection:FNab06090 1:1000) with HeLa cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06090(p70(S6K) Antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells using FNab06090 ( p70S6K Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Background
- RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
