Products
p38 antibody
- Product Name
- p38 antibody
- Catalogue No.
- FNab06076
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitogen-activated protein kinase 14
- Alternative Names
- CSAID binding protein antibody, CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, MAP kinase 14 antibody, MAP kinase MXI2 antibody, MAP kinase p38 alpha antibody, MAPK 14 antibody, MAPK14 antibody, MAX interacting protein 2 antibody, Mxi2 antibody, p38 antibody, p38ALPHA antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody
- UniProt ID
- Q16539
- Observed MW
- 41 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:20-1:200; IHC: 1:50-1:500
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab06076(p38 MAPK Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using FNab06076(p38 Antibody) at dilution of 1:200
Immunofluorescent analysis of ( 4% PFA ) fixed HepG2 cells using FNab06076( p38 MAPK Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
