Products
Osteopontin antibody
- Product Name
- Osteopontin antibody
- Catalogue No.
- FNab06033
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- secreted phosphoprotein 1
- Alternative Names
- BNSP antibody, Bone sialoprotein 1 antibody, BSPI antibody, ETA 1 antibody, Nephropontin antibody, OPN antibody, Osteopontin antibody, secreted phosphoprotein 1 antibody, SPP 1 antibody, SPP1 antibody, Urinary stone protein antibody, Uropontin antibody
- UniProt ID
- P10451
- Observed MW
- 66 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab06033(OPN Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06033(OPN antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells using FNab06033 (Osteopontin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Osteopontin(OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues(PMID: 15138464; 16406521). OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.
