Products
ORAI1 antibody
- Product Name
- ORAI1 antibody
- Catalogue No.
- FNab06002
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 8C0
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ORAI calcium release-activated calcium modulator 1
- Alternative Names
- CRACM1 antibody, FLJ14466 antibody, ORAI1 antibody, ORAI1 L1 antibody, ORAI1 L2 antibody, Orail L2 antibody, ORAT1 antibody, Protein orai 1 antibody, TMEM142A antibody, Transmembrane protein 142A antibody
- UniProt ID
- Q96D31
- Observed MW
- 32 kDa
Application
- Tested Applications
- ELISA, WB,IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab06002(ORAI1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06002(ORAI1 Antibody) at dilution of 1:200
- Background
- Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
