OLFM2 antibody

Synonyms:NOE2 antibody
Catalogue No.:FNab05984Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
OLFM2 antibody
Catalogue No.
FNab05984
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
olfactomedin 2
Alternative Names
NOE2 antibody
UniProt ID
O95897
Observed MW
51kd
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab05984(OLFM2 antibody) at dilution of 1:500
Background
Involved in transforming growth factor beta(TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes(PubMed:25298399). Plays a role in AMPAR complex organization(By similarity).