ODF2 antibody

Catalogue No.:FNab05971Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ODF2 antibody
Catalogue No.
FNab05971
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
outer dense fiber of sperm tails 2
UniProt ID
Q5BJF6
Observed MW
67-100 kDa
Application
Tested Applications
ELISA, WB, IHC, IP, IF
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05971(ODF2 antibody) at dilution of 1:500
IP Result of anti-ODF2 (IP:FNab05971, 5ug; Detection:FNab05971 1:500) with mouse testis tissue lysate 8000ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab05971(ODF2 antibody) at dilution of 1:50
Background
Seems to be a major component of sperm tail outer dense fibers(ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.