Products
NXF1 antibody
- Product Name
- NXF1 antibody
- Catalogue No.
- FNab05941
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear RNA export factor 1
- Alternative Names
- MEX67 antibody, mRNA export factor TAP antibody, nuclear RNA export factor 1 antibody, NXF1 antibody, TAP antibody, Tip associated protein antibody, Tip associating protein antibody
- UniProt ID
- Q9UBU9
- Observed MW
- 66-70 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB : 1:500-1:1000; IHC : 1:20-1:200; IF : 1:20-1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab05941( NXF1 Antibody) at dilution of 1:600
Immunofluorescent analysis of HepG2 cells using FNab05941 (NXF1 antibody) at dilution of 1:50
- Background
- Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements(CTE) and in the export of mRNA from the nucleus to the cytoplasm(TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.
