Products
NUP153 antibody
- Product Name
- NUP153 antibody
- Catalogue No.
- FNab05921
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nucleoporin 153kDa
- UniProt ID
- P49790
- Observed MW
- 153 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab05921(NUP153 antibody) at dilution of 1:500
IP Result of anti-NUP153 (IP:FNab05921, 4ug; Detection:FNab05921 1:500) with K-562 cells lysate 3600ug.
- Background
- Component of the nuclear pore complex(NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element(CTE) in a NXF1-and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex(NPC).
