NUDT3 antibody

Synonyms:DIPP antibody, DIPP1 antibody
Catalogue No.:FNab05905Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NUDT3 antibody
Catalogue No.
FNab05905
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
nudix(nucleoside diphosphate linked moiety X)-type motif 3
Alternative Names
DIPP antibody, DIPP1 antibody
UniProt ID
O95989
Observed MW
20-30kd
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05905(NUDT3 antibody) at dilution of 1:2000
Background
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.