Products
NT5E/CD73 antibody
- Product Name
- NT5E/CD73 antibody
- Catalogue No.
- FNab05878
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- 5'-nucleotidase, ecto(CD73)
- Alternative Names
- 5 NT antibody, 5 nucleotidase antibody, 5' nucleotidase antibody, ecto(CD73) antibody, CD73 antibody, E5NT antibody, Ecto 5 nucleotidase antibody, eN antibody, eNT antibody, NT antibody, NT5 antibody, NT5E antibody, NTE antibody
- UniProt ID
- P21589
- Observed MW
- 63 kDa
Application
- Tested Applications
- ELISA, WB,IHC,FC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05878(NT5E,CD73 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab05878(NT5E,CD73 Antibody) at dilution of 1:200
- Background
- NT5E(5'-nucleotidase) is also named as NT5, NTE,CD73,ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling(PMID:17619139). This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer(PMID:17619139). It can be detected the band of 55 kDa,64 kDa, 70 kDa, 110 kDa by western blot(PMID:17619139; 12370277; 21533188). Defects in NT5E are the cause of calcification of joints and arteries(CALJA).
