Products
NR3C2 antibody
- Product Name
- NR3C2 antibody
- Catalogue No.
- FNab05846
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear receptor subfamily 3, group C, member 2
- Alternative Names
- MCR antibody, Mineralocorticoid receptor antibody, MLR antibody, MR antibody, NR3C2 antibody
- UniProt ID
- P08235
- Observed MW
- 107 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05846(NR3C2 antibody) at dilution of 1:1000
IP Result of anti-NR3C2 (IP:FNab05846, 4ug; Detection:FNab05846 1:500) with HEK-293 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab05846(NR3C2 antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells, using NR3C2 antibody FNab05846 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- Receptor for both mineralocorticoids(MC) such as aldosterone and glucocorticoids(GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements(MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
