NPLOC4 antibody

Synonyms:KIAA1499 antibody, NPL4 antibody
Catalogue No.:FNab05821Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NPLOC4 antibody
Catalogue No.
FNab05821
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
nuclear protein localization 4 homolog
Alternative Names
KIAA1499 antibody, NPL4 antibody
UniProt ID
Q8TAT6
Observed MW
68kd
Application
Tested Applications
ELISA, WB, IP, IHC
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab05821(NPLOC4 antibody) at dilution of 1:200
IP Result of anti-NPLOC4 (IP:FNab05821, 4ug; Detection:FNab05821 1:600) with mouse kidney tissue lysate 6000ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05821(NPLOC4 Antibody) at dilution of 1:50
Background
The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope(By similarity).