Products
nNOS antibody
- Product Name
- nNOS antibody
- Catalogue No.
- FNab05774
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nitric oxide synthase 1(neuronal)
- Alternative Names
- bNOS antibody, Constitutive NOS antibody, IHPS1 antibody, N NOS antibody, NC NOS antibody, Neuronal NOS antibody, Nitric oxide synthase antibody, brain antibody, nNOS antibody, NOS antibody, NOS type I antibody, NOS1 antibody
- UniProt ID
- P29475
- Observed MW
- 161kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05774(nNOS antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05774(nNOS Antibody) at dilution of 1:50
- Background
- nNOS belongs to the NOS family. NOS1 produces nitric oxide(NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1(IHPS1).The antibody can recognize isoform 1,2,4,5 of NOS1.
