Products
NIT1 antibody
- Product Name
- NIT1 antibody
- Catalogue No.
- FNab05741
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nitrilase 1
- UniProt ID
- Q86X76
- Observed MW
- 36kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab05741(NIT1 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab05741(NIT1 antibody) at dilution of 1:50
- Background
- Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2(By similarity).
