Products
NGB antibody
- Product Name
- NGB antibody
- Catalogue No.
- FNab05718
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- neuroglobin
- Alternative Names
- NGB antibody, neuroglobin antibody
- UniProt ID
- Q9NPG2
- Observed MW
- 16kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab05718(NGB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab05718(NGB antibody) at dilution of 1:100
- Background
- Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
