Products
NFIL3 antibody
- Product Name
- NFIL3 antibody
- Catalogue No.
- FNab05700
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear factor, interleukin 3 regulated
- Alternative Names
- E4BP4 antibody, IL3BP1 antibody
- UniProt ID
- Q16649
- Observed MW
- 55-60 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab05700(NFIL3 antibody) at dilution of 1:3000
IP Result of anti-NFIL3 (IP:FNab05700, 4ug; Detection:FNab05700 1:1000) with HeLa cells lysate 1600ug.
- Background
- Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).
