NFAM1 antibody

Synonyms:CNAIP antibody
Catalogue No.:FNab05689Reactivity:Human
Host:RabbitTested Application:ELISA, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NFAM1 antibody
Catalogue No.
FNab05689
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
NFAT activating protein with ITAM motif 1
Alternative Names
CNAIP antibody
UniProt ID
Q8NET5
Application
Tested Applications
ELISA, IHC
Recommended dilution
IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab05689(NFAM1 Antibody) at dilution of 1:50
Background
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.