Products
NELFB antibody
- Product Name
- NELFB antibody
- Catalogue No.
- FNab05657
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cofactor of BRCA1
- Alternative Names
- COBRA1 antibody, KIAA1182 antibody
- UniProt ID
- Q8WX92
- Observed MW
- 66 kDa
Application
- Tested Applications
- ELISA, WB, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Validated Images
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab05657( NELFB antibody） at dilution of 1:1000
IP Result of anti-NELFB (IP:FNab05657, 3ug; Detection:FNab05657 1:500) with mouse brain tissue lysate 6000ug.
- Background
- Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
