Products
NCOA3 antibody
- Product Name
- NCOA3 antibody
- Catalogue No.
- FNab05589
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear receptor coactivator 3
- Alternative Names
- AIB1 antibody, BHLHE42 antibody, RAC3 antibody, TRAM1 antibody
- UniProt ID
- Q9Y6Q9
- Observed MW
- 160kd
Application
- Tested Applications
- ELISA, WB, IF, IHC, FC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05589(NCOA3 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab05589(NCOA3 Antibody) at dilution of 1:50
- Background
- Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ER), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
