A431 cells were subjected to SDS PAGE followed by western blot with FNab05482 (MYH9 antibody) at dilution of 1:2000
Background
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation(in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.