Products
MUS81 antibody
- Product Name
- MUS81 antibody
- Catalogue No.
- FNab05441
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- MUS81 endonuclease homolog
- UniProt ID
- Q96NY9
- Observed MW
- 52-72 kDa
Application
- Tested Applications
- ELISA, IHC, IF
- Recommended dilution
- IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05441(MUS81 Antibody) at dilution of 1:400
- Background
- Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
