human liver tissue were subjected to SDS PAGE followed by western blot with FNab05431(MUC20 antibody) at dilution of 1:400
Background
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor(HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.