MUC20 antibody

Synonyms:KIAA1359 antibody
Catalogue No.:FNab05431Reactivity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
MUC20 antibody
Catalogue No.
FNab05431
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
mucin 20, cell surface associated
Alternative Names
KIAA1359 antibody
UniProt ID
Q8N307
Observed MW
70-75kd
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab05431(MUC20 antibody) at dilution of 1:400
Background
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor(HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.