Products
MTM1 antibody
- Product Name
- MTM1 antibody
- Catalogue No.
- FNab05406
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- myotubularin 1
- Alternative Names
- CG2 antibody
- UniProt ID
- Q13496
- Observed MW
- 63 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
L02 cells were subjected to SDS PAGE followed by western blot with FNab05406(MTM1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human osteosarcoma using FNab05406(MTM1 antibody) at dilution of 1:100
- Background
- Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate(PI3P) and phosphatidylinositol 3,5-bisphosphate(PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine-and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
