MMADHC antibody

Category: Research Area:
Synonyms：C2orf25 antibody, CL25022 antibody
Catalogue No.：FNab05228Reactivity：Human
Host：RabbitTested Application：ELISA, IHC, WB
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
MMADHC antibody
Catalogue No.
FNab05228
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
methylmalonic aciduria(cobalamin deficiency) cblD type, with homocystinuria
Alternative Names
C2orf25 antibody, CL25022 antibody
UniProt ID
Q9H3L0
Observed MW
33 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05228(MMADHC Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab05228(MMADHC Antibody) at dilution of 1:200
Background
Involved in cobalamin metabolism(PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851). Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin(PubMed:18385497, PubMed:24722857). Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin(PubMed:23415655, PubMed:24722857). Promotes oxidation of cob(II)alamin bound to MMACHC(PubMed:26364851).
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