MIB2 antibody

Synonyms:SKD antibody, ZZANK1 antibody
Catalogue No.:FNab05175Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
MIB2 antibody
Catalogue No.
FNab05175
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
mindbomb homolog 2(Drosophila)
Alternative Names
SKD antibody, ZZANK1 antibody
UniProt ID
Q96AX9
Observed MW
74 kDa, 82 kDa, 110 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500 - 1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab05175(MIB2 antibody) at dilution of 1:1000
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors(By similarity).