Products
MEK1 antibody
- Product Name
- MEK1 antibody
- Catalogue No.
- FNab05112
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitogen-activated protein kinase kinase 1
- Alternative Names
- ERK activator kinase 1 antibody, MAP kinase kinase 1 antibody, MAP2K1 antibody, MAPK/ERK kinase 1 antibody, MAPKK 1 antibody, MAPKK1 antibody, MEK 1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody
- UniProt ID
- Q02750
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
mouse brain were subjected to SDS PAGE followed by western blot with FNab05112(MEK1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat lung using FNab05112(MEK1 antibody) at dilution of 1:100
- Background
- MEK1 is also named as MAP2K1(mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated.
