Products
MED12 antibody
- Product Name
- MED12 antibody
- Catalogue No.
- FNab05087
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mediator complex subunit 12
- Alternative Names
- ARC240 antibody, CAGH45 antibody, HOPA antibody, KIAA0192 antibody, TNRC11 antibody, TRAP230 antibody
- UniProt ID
- Q93074
- Observed MW
- 230 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05087(MED12 antibody) at dilution of 1:800
- Background
- Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
