Products
MCM2 antibody
- Product Name
- MCM2 antibody
- Catalogue No.
- FNab05057
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 4E3
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- minichromosome maintenance complex component 2
- Alternative Names
- BM28 antibody, CCNL1 antibody, CDCL1 antibody, KIAA0030 antibody
- UniProt ID
- P49736
- Observed MW
- 116-125 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:1000-1:2000
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab05057( MCM2 Antibody) at dilution of 1:2000
- Background
- Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
