Products
MCM2 antibody
- Product Name
- MCM2 antibody
- Catalogue No.
- FNab05056
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- minichromosome maintenance complex component 2
- Alternative Names
- BM28 antibody, CCNL1 antibody, CDCL1 antibody, KIAA0030 antibody
- UniProt ID
- P49736
- Observed MW
- 116-125 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab05056(MCM2 antibody) at dilution of 1:1000
IP Result of anti-MCM2 (IP:FNab05056, 4ug; Detection:FNab05056 1:800) with HEK-293 cells lysate 2800ug.
Immunohistochemistry of paraffin-embedded human placenta tissue slide using FNab05056(MCM2 Antibody) at dilution of 1:50
- Background
- Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
