Products

MBNL3 antibody

Synonyms:CHCR antibody, MBLX39 antibody, MBXL antibody
Catalogue No.:FNab05041Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
MBNL3 antibody
Catalogue No.
FNab05041
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
muscleblind-like 3(Drosophila)
Alternative Names
CHCR antibody, MBLX39 antibody, MBXL antibody
UniProt ID
Q9NUK0
Observed MW
38 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05041(MBNL3 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab05041(MBNL3 Antibody) at dilution of 1:50
Background
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.