Products
MARCH8 antibody
- Product Name
- MARCH8 antibody
- Catalogue No.
- FNab05004
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- membrane-associated ring finger(C3HC4) 8
- Alternative Names
- MIR antibody, RNF178 antibody
- UniProt ID
- Q5T0T0
- Observed MW
- 33kd
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:200-1:1000
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05004(MARCH8 antibody) at dilution of 1:800
IP Result of anti-MARCH8 (IP:FNab05004, 3ug; Detection:FNab05004 1:400) with mouse lung tissue lysate 4000ug.
- Background
- E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
