Products
MAD2L1 antibody
- Product Name
- MAD2L1 antibody
- Catalogue No.
- FNab04923
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- MAD2 mitotic arrest deficient-like 1(yeast)
- Alternative Names
- HSMAD2 antibody, MAD2 antibody, MAD2 like protein 1 antibody, MAD2L1 antibody
- UniProt ID
- Q13257
- Observed MW
- 25-30 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04923(MAD2L1 antibody) at dilution of 1:800
IP Result of anti-MAD2L1 (IP:FNab04923, 3ug; Detection:FNab04923 1:500) with HEK-293 cells lysate 1800ug.
Immunohistochemistry of paraffin-embedded human liver cancer using FNab04923(MAD2L1 antibody) at dilution of 1:50
- Background
- Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
