U-937 cells were subjected to SDS PAGE followed by western blot with FNab04900(LY96 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human kidney using FNab04900(LY96 antibody) at dilution of 1:50
Immunofluorescent analysis of U2OS cells using FNab04900 (LY96 antibody) at dilution of 1:50
Background
Binds bacterial lipopolysaccharide(LPS)(PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide(LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria(PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B(PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS(PubMed:10359581).