Products

anti- LRWD1 antibody

FNab04867 Catalogue No.
Synonyms
CENP-33, ORCA
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- LRWD1 antibody
Catalogue No.
FNab04867
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Immunogen Information
Immunogen
leucine-rich repeats and WD repeat domain containing 1
Synonyms
CENP-33, ORCA
Observed MW
85 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Uniprot information
UniProt ID
Q9UFC0
Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab04867(LRWD1 antibody) at dilution of 1:100