Products
LRRC8C antibody
- Product Name
- LRRC8C antibody
- Catalogue No.
- FNab04861
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- leucine rich repeat containing 8 family, member C
- Alternative Names
- AD158 antibody, FAD158 antibody
- UniProt ID
- Q8TDW0
Application
- Tested Applications
- ELISA, IF, IHC
- Recommended dilution
- IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human heart using FNab04861(LRRC8C antibody) at dilution of 1:50
- Background
- Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
