Products
LPXN antibody
- Product Name
- LPXN antibody
- Catalogue No.
- FNab04837
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- leupaxin
- Alternative Names
- LDLP antibody
- UniProt ID
- O60711
- Observed MW
- 50-60 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab04837(LPXN Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human prostate cancer slide using FNab04837(LPXN Antibody) at dilution of 1:50
- Background
- Transcriptional coactivator for androgen receptor(AR) and serum response factor(SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin(PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor(BCR) signaling.
