human lung tissue were subjected to SDS PAGE followed by western blot with FNab04825(LPCAT1 antibody) at dilution of 1:4000
IP Result of anti-LPCAT1 (IP:FNab04825, 3ug; Detection:FNab04825 1:4000) with mouse brain tissue lysate 3600ug.
Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab04825(LPCAT1 Antibody) at dilution of 1:100
Background
Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).