LPCAT1 antibody

Synonyms:AYTL2 antibody, PFAAP3 antibody
Catalogue No.:FNab04825Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IF, WB, IP, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
LPCAT1 antibody
Catalogue No.
FNab04825
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
lysophosphatidylcholine acyltransferase 1
Alternative Names
AYTL2 antibody, PFAAP3 antibody
UniProt ID
Q8NF37
Observed MW
59 kDa
Application
Tested Applications
ELISA, IF, WB, IP, IHC
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human lung tissue were subjected to SDS PAGE followed by western blot with FNab04825(LPCAT1 antibody) at dilution of 1:4000
IP Result of anti-LPCAT1 (IP:FNab04825, 3ug; Detection:FNab04825 1:4000) with mouse brain tissue lysate 3600ug.
Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab04825(LPCAT1 Antibody) at dilution of 1:100
Background
Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).