Y79 cells were subjected to SDS PAGE followed by western blot with FNab04793(LIPA antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human colon cancer using FNab04793(LIPA antibody) at dilution of 1:100
Background
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL(low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.