Products
LIPA antibody
- Product Name
- LIPA antibody
- Catalogue No.
- FNab04793
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- lipase A, lysosomal acid, cholesterol esterase
- UniProt ID
- P38571
- Observed MW
- 45kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Y79 cells were subjected to SDS PAGE followed by western blot with FNab04793(LIPA antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human colon cancer using FNab04793(LIPA antibody) at dilution of 1:100
- Background
- Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL(low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
