Products

Lin28B-specific antibody

Synonyms:CSDD2 antibody, FLJ16517 antibody, lin 28 homolog B(C. elegans) antibody, Lin 28B antibody, Lin28 antibody, LIN28B antibody, Protein lin 28 homolog B antibody
Catalogue No.:FNab04786Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Lin28B-specific antibody
Catalogue No.
FNab04786
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
lin-28 homolog B(C. elegans)
Alternative Names
CSDD2 antibody, FLJ16517 antibody, lin 28 homolog B(C. elegans) antibody, Lin 28B antibody, Lin28 antibody, LIN28B antibody, Protein lin 28 homolog B antibody
UniProt ID
Q6ZN17
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04786(Lin28B-specific Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain using FNab04786(Lin28B-specific antibody) at dilution of 1:50
Background
LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA(miRNA) biogenesis by specifically binding the precursor let-7(pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.