anti- LIG4 antibody
FNab04774
Catalogue No.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC
Product Information
- Product Name
- anti- LIG4 antibody
- Catalogue No.
- FNab04774
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
- Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Immunogen Information
- Immunogen
- ligase IV, DNA, ATP-dependent
- Observed MW
- 100-104 kDa
Application
- Tested Application
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Uniprot information
- UniProt ID
- P49917
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab04774 (LIG4 antibody) at dilution of 1:100
- Image 4
-
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab04774 (LIG4 antibody) at dilution of 1:600