Products
LDLR antibody
- Product Name
- LDLR antibody
- Catalogue No.
- FNab04742
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- low density lipoprotein receptor
- Alternative Names
- FH antibody, FHC antibody, LDL receptor antibody, LDLR antibody
- UniProt ID
- P01130
- Observed MW
- 150-160 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04742(LDLR antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab04742(LDLR Antibody) at dilution of 1:200 heat mediated antigen retrieved with Sodium Citrate buffer(pH6).
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using FNab04742 (LDLR antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
