rat brain tissue were subjected to SDS PAGE followed by western blot with FNab04720( MAP1LC3B-Specific Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab04720(LC3B-Specific antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using MAP1LC3B antibody (FNab04720). Blue: DAPI for nuclear staining.
Background
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.