Products
Cleaved LC3 antibody
- Product Name
- Cleaved LC3 antibody
- Catalogue No.
- FNab04716
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- microtubule-associated protein 1 light chain 3 alpha
- Alternative Names
- LC3 antibody, LC3A antibody, LC3A/B antibody, MAP1A/MAP1B LC3 A antibody, MAP1A/MAP1B light chain 3 A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, MAP1LC3A antibody
- UniProt ID
- Q9H492
- Observed MW
- Refer to Figures
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Chloroquine treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab04716 (LC3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04716( LC3 antibody) at dilution of 1:200
- Background
- MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
