HeLa cells were subjected to SDS PAGE followed by western blot with FNab04700(LARP7 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney using FNab04700(LARP7 antibody) at dilution of 1:100
Background
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b(P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.