mouse small intestine tissue were subjected to SDS PAGE followed by western blot with FNab04670(L2HGDH antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab04670( L2HGDH Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.