Products
KLHL21 antibody
- Product Name
- KLHL21 antibody
- Catalogue No.
- FNab04619
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- kelch-like 21(Drosophila)
- Alternative Names
- KIAA0469 antibody
- UniProt ID
- Q9UJP4
- Observed MW
- 67kd
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab04619(KLHL21 antibody) at dilution of 1:400
IP Result of anti-KLHL21 (IP:FNab04619, 3ug; Detection:FNab04619 1:300) with HeLa cells lysate 1800ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab04619(KLHL21 Antibody) at dilution of 1:50
- Background
- Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex(CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
